Peptide Dose Calculator

Retatrutide reconstitution calculator

Units = dose (mg) × mL of solution ÷ mg in the vial × 100. Pick the vial size, enter how much liquid is in it and the dose you've been given. The calculator shows the units on a U-100 syringe and every step of the math. It doesn't suggest a dose or a dilution.

Converts a dose you already have; it does not recommend one. How we check our work Sources

Investigational medicine. Retatrutide is not FDA approved. See FDA information on unapproved GLP-1 drugs. (opens in a new tab)
Vial size:
mL

Use the final solution volume in mL. Water added is an approximation of that volume.

How the math works

concentration (mg/mL) = mg in the vial ÷ total solution (mL) volume to draw (mL) = dose (mg) ÷ concentration units (U-100) = volume (mL) × 100

Nothing in the formula is specific to retatrutide. Two vials of the same size give different answers if they hold different amounts of liquid, which is why a dose in "units" means nothing without the vial size and the volume. If your dose is in micrograms, divide by 1,000 first: 500 mcg is 0.5 mg.

How much bac water for a 10 mg vial?

Mathematically there's no right answer: the liquid added only sets the concentration. What changes is how many units each milligram takes up on the syringe:

  • 1 mL: 10 mg/mL, so each 1 mg is 0.1 mL = 10 units
  • 2 mL: 5 mg/mL, so each 1 mg is 0.2 mL = 20 units
  • 3 mL: 3.33 mg/mL, so each 1 mg is 0.3 mL = 30 units

More liquid spreads the same milligrams over more units, so small amounts sit on more syringe lines and are easier to read, but every dose takes more volume. Less liquid does the opposite. The volume to use should come from the instructions supplied with the vial or from a pharmacist; this page only shows what each choice means in units.

Tables for common vial sizes

Find your vial size in the rows and the total solution volume in the columns. To get units for your dose, multiply the second table's number by the dose in mg: 2.5 mg from a 10 mg vial with 2 mL is 2.5 × 20 = 50 units.

Concentration in mg/mL, by vial size and total solution volume
Vial1 mL1.5 mL2 mL2.5 mL3 mL
5 mg53.3332.521.667
10 mg106.667543.333
12 mg12864.84
15 mg15107.565
20 mg2013.3331086.667
24 mg2416129.68
30 mg3020151210
U-100 units for each 1 mg, by vial size and total solution volume
Vial1 mL1.5 mL2 mL2.5 mL3 mL
5 mg2030405060
10 mg1015202530
12 mg8.3312.516.6720.8325
15 mg6.671013.3316.6720
20 mg57.51012.515
24 mg4.176.258.3310.4212.5
30 mg3.3356.678.3310

Values are rounded for display; the calculator works from the unrounded numbers. Volumes assume the total solution is the water added, which is a close approximation.

What "reconstituting" changes in the math

Freeze-dried vials hold powder until liquid is added. The amount of liquid is the only part of reconstitution that changes the arithmetic: it fixes the concentration for the life of the vial. If you're unsure how much liquid a vial holds, don't guess from the label size; ask the pharmacist who supplied it. How to add the liquid, keep it sterile and store it are questions for a pharmacist, not a calculator.

Retatrutide's status

Retatrutide is investigational. It's an experimental medicine from Eli Lilly that acts on the GIP, GLP-1 and glucagon receptors, and it has been tested in phase 2 and phase 3 trials. As of November 2026 the FDA hasn't approved it for any use. Products sold online as retatrutide or "GLP-3" aren't the medicine used in the trials, and nothing confirms what they contain or how much. This calculator does arithmetic on numbers you enter; it can't make an unverified vial safe.

Questions

How many units is 1 mg of retatrutide?

It depends on the vial and the volume, not on retatrutide itself. From a 10 mg vial holding 2 mL (5 mg/mL), 1 mg is 0.2 mL, or 20 units. From the same vial holding 1 mL, it's 10 units; holding 3 mL, it's 30 units. The table above lists every common combination.

How much bac water for a 10 mg retatrutide vial?

There's no single correct amount in the math: the volume you add sets the concentration. 1 mL gives 10 mg/mL, 2 mL gives 5 mg/mL and 3 mL gives about 3.33 mg/mL. The amount should come from the instructions supplied with the vial or from a pharmacist. Once you know it, the calculator turns your dose into units.

How many units is 2 mg from a 12 mg vial?

With 2 mL of solution the vial is 6 mg/mL, so 2 mg is 2 ÷ 6 = 0.333 mL, or 33.3 units. With 3 mL it's 4 mg/mL, so 2 mg is 0.5 mL, or 50 units. Enter your own numbers above to check.

Is retatrutide FDA approved?

No. As of November 2026 retatrutide is an investigational medicine from Eli Lilly and isn't approved by the FDA for any use. Lilly has said it plans to apply for approval in 2027. Products sold online as retatrutide are not the approved or trial medicine, and their contents aren't verified.

Is GLP-3 the same as retatrutide?

"GLP-3" is an informal nickname, often used by sellers, not a scientific name. There's no GLP-3 hormone. Retatrutide acts on three receptors, GIP, GLP-1 and glucagon, which is where the "3" comes from. A product's nickname tells you nothing about what's in the vial.

Does the calculator include trial doses?

No. Trial doses describe what participants received in a study under medical supervision; they aren't a schedule for anyone else. Doses here are always the number you type in.